The idea of prison even though initially was largely punitive to offenders, lawbreakers, criminals and other social deviants in the society, attention in the contemporary era shifted to how prisoners could reform for the better, to properly fit into society. This study was conducted assess the influence of pastoral care on Ghanaian inmates in the Kumasi central prison. The specific objectives were to identify the forms of pastoral care services in the prisons, effects of the pastoral care in the reformation of lives of the prisoners, and the pastoral care interventions and techniques used by the pastors in the prisons. A case study design was conducted using purposive sampling technique to select a sample size of 24 participants. The main data collection instrument was in-depth interview (IDI). The data were analysed using content analysis with the aid of NVivo. The study found that pastoral care is done in a group inside the prison’s church, and the forms include cognitive-behavioral therapy, vocational counseling, the message of repentance and salvation, substance abuse, aids, and advice, among others. The study revealed that pastoral care has a positive influence on the reformation and transformation of prisoners' lives by addressing some of the physical, spiritual and emotional needs of inmates, which can contribute to their overall well-being and personal transformation. The study found that the pastors usually tailor their interventions and techniques toward the general needs of inmates, such as food, toiletries, security, messages of hope, and other aids that attract the prisoners to draw closer and to receive their messages of salvation and advice. The study recommends that policymakers and prison authorities should encourage more pastoral care services in group settings to reach more inmates and provide them with emotional and spiritual support.